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Re: Combinatorial Library Enumeration [message #1320 is a reply to message #1317] Tue, 22 June 2021 22:21 Go to previous message
nbehrnd is currently offline  nbehrnd
Messages: 233
Registered: June 2019
Senior Member
Dear ndandu,

the generation of the reaction map requires one complete reaction. Thus, in the explicit reaction of the anhydride with methylamine, the amide must include the methyl group, too. Subsequently, map remaining atoms of the anhydride in the product, followed by those inherited by the amine. The short .mp4 attached below might illustrate this further.

Norwid
 
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