idcoordinates2D FragFp Assay Index Structure MolRegNo m Value Unit Type Ligand Efficiency Binding Efficiency Surface Efficiency Assay Category Assay Organism Target ID Target Name Target Organism Target Description Sequence Accession Reference Pubmed ID DOI Scaffold R1 R2 R3 R4 R5 R6 R7 !BhBw@ja\mtA@Iz@dCVw@gzmpJ`^amd}Cazgx@mwtw_j`~bC@ioyP@z[YLhPPg^@@WsH`g\@`X@APg\ =vzv;WzyvzXf5IzvdHiqz@CnkisvRe7gnb9DlnDF5eZAQW9BqTu4kQtJY3N12QcBcJ03mG61J0n$V 46896 e`ZTL@@KE`FolbbbbbTTTVRNfcTRRgfedUVWSPswsPR@E@ADUUTPU@UP@@ 374473 = 0.3 nM Ki 0.41 22.33 21.79 |#|0:46896 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ dcNDPJAY@M@DiWV\jjjjjcb@@ eFBH@c@@ dcNDPJAY@M@DiWV\jjjjjcb@@ dk\H`@p@rJJZIQDYtv`@@@@@ !BpEeTQIh_iVCSY~CewzZlYpEBOreXBn{yQp@x`CUHQ_qc|fuKlAox`BpMekn~T_mw_FUR{yQ}e[uR{ =vUxzpxtMRuzDQ0nYNem66TGC3VuBUtX7VX11Nkf611X02SW1VJTcRkOdMl2k17@V4cJ11Z141J0b0W0FV 46894 eodRB@@DJAA`@bglbbTRTTRRbRfVUfRDd|jRzn^Zfh@``hbjj``@@ 102928 = 77 nM Ki 0.31 16.76 9.14 |#|0:46894 Homo sapiens 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`qPC`FZ@DdpQDJgFrB{q}@iLs\s{rVcPQDUUB@@ difH`J@PAJUuJjjj`@ eMJA@Hz@ dknD`D@\@Df]fUTvjBB@@@ !BpEeTQIh_iVCSY~CeeHS_ijqg@W|HBCYiVBeXBn{yQp@x`CEHQTaEFOr[TnpFb@JehFn{yQ~w]|YUKoeGvUoUKl =vUxzpxtrRvzEQ0nYOuq66TGC3VvgUtX7VXW1Nkf615X02SW1VJygRktdMlXk1M@V4cJ11Z141J0Y0W0Fk 46894 el^ZL@@DJICC`Ad\bbTTRbbbRRRRfvUfRdTRfJVZvaQZfj@@`@J@jjhB@@@ 104444 = 146 nM Ki 0.27 14.50 8.39 |#|0:46894 Homo sapiens 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`qPC`FZ@DdpQDJgFrB{q}@iLs\s{rVcPQDUUB@@ difH`J@PAJUuJjjj`@ eMJA@Hz@ fhiQB@D\A`@RYyfUWMypVj`@@@@@@ !BeWQ_QiRDY^@knzU`W{hTaIh_Zsl`vU|ffa~ZGrAzTv]`yZqg@W~HFT_B@NH@sR{k~H@fT_muTns|YyV~eG}}Y =vUxzpxtrRvzEQ1nYOuq6DTICYXvgUxX7VXY1Plf6G9X02SW1gJycRkvdMlYl37@VBcJ11ZG41J0Y4180V 46894 edZRLD@I@dmcIhPHcbPrJJIQVJJZEQIISKSILBIY]K@ppDQTuMAAQUUDP@@ 104479 = 69 nM Ki 0.29 14.64 11.97 |#|0:46894 Homo sapiens 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`qPC`FZ@DdpQDJgFrB{q}@iLs\s{rVcPQDUUB@@ difH`J@PAJUuJjjj`@ eMJA@Hz@ f`aaC@IFAD\dK@FQQQJJqQQ`hBHjZ`@@ !Btz\ccIOtv]MTENgxNWRS{~N[N\A_p`BCUBSY~T_|OvH_RrXoxycmQ{@W~H@`Aqtv_eG{]}UKo_FVWoyQ_fP =fUSzpxtURAzEQ0lfOeHaDP1CYVeBzxX7cX59Pkf6F1X02SW9ZJTsBkvdMl3l13AVBcJ11o1J1J0b4#V 46894 ehZ\B@@DEE`Df`\bbbbRTtRRbRfVUfRXDTtbzJf~AZif`BBBbJjj``@@ 103723 = 67 nM Ki 0.30 16.03 12.40 |#|0:46894 Homo sapiens 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ difH`J@PAJUuJjjj`@ f`a`a@D@u`@D@ILvk\k[sUMAA@BED eMJA@Hz@ f`a`a@D@u`@D@ILvk\k[sUMAA@BED !BpEeTQIh_iVC`y]MgOzZTa@EB@JlYw}~`dBexBn{yVBdiHa}|@NH@~T_[^Ta@FbGsTnw~mwweGuR{wqee[~T_wud =v;x;yvzDfUvzvzUTUvfjrkjxzxnEun_hDIjE0EjgaS_8FTyuDoQfKnXm53AkJdRF9p141JVY0V0FV 46886 el^\L@@DMK`Ad\bbTTTTTbdRRsfVqbRdtlBBzJfaQZihJjjBjJjjjbPxPT@@ 103930 = 6 % Inhibition |#|0:46886 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ difH`J@PAJUuJjjj`@ gC`HL@IST@@ eMJA@Hz@ dg~H`DC@AIgffoeVvjjjjdiK@@ !BpEeTQIh_iVC`y]MgOzZTa@EB@JlYw}~`dBexBn{yVBdiHa}|@NH@~T_eHPAoxa|uKnw_^T_UKo_FVUoyQ_VP =v;xzvzyvzDfUvzvzMTLvfjrkjxztn7un_hDGjE0Cjg6S_8FTyuDoOdKlXm53AkJdRF9p141JVY0V0FV 46894 ehZ\L@@DMM`N`\bbTTTTTbdRQ\vvbRdtlBBZJF~AZihJjjBhjjjhdNDE@@ 103887 = 29 nM Ki 0.31 16.62 13.53 |#|0:46894 Homo sapiens 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ difH`J@PAJUuJjjj`@ eFBH@c@@ eMJA@Hz@ dg~H`DC@AIgffoeVvjjjjdiK@@ !Btz\ccIOTv^MTINgXNTrSrrX_xylyyb@I@\TtpCUBSY~T_bGvH\rXKIbck~NUGlA_x`BSUCSY~T_mwuTn}|Yi^}eGs~Y =vUSzpxtzRAzEQ1lfOuLaDPGCYVfgzxX7cXb9Pkf6FCX02SW9gJywRkvdKlYl1MAVBcJ11oGJ1J0Y4#k 46887 ejURL@@DMGG`Eb\bbbbTRfbbRRRRfvUfRXDtLJvZNFnqIZifh@B@@hBjjhB@@@ 103697 = 13 % Inhibition |#|0:46887 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ difH`J@PAJUuJjjj`@ fbuQA@DJA`@d@ILvrsZk~SGKUMP@@@@HTP eMJA@Hz@ fbuQA@DJA`@d@ILvrsZk~SGKUMP@@@@HTP !BpEfTQIh_iVCSYvCeOzYTaBqgg~HHI@i^@knvU`BOvdiNT_b@NH@uSxUKlAox`ByQ~w_]|YUKmeGzUoUKl =v;xzvzyvzDvUvzvzrTLzvjMkzxUtn7mnW_BGjE1Cjg6S_0FTyeToOdMlXm57@kJdRF9_141JVY0W0FV 46894 e`RRL@@DJII`NolbbTTRbdTbRsTJtrTbaggeQPswsTuPUUPUEUUTRGB|`@ 102929 = 2 nM Ki 0.37 19.74 12.68 |#|0:46894 Homo sapiens 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`qPC`FZ@DdpQDJgFrB{q}@iLs\s{rVcPQDUUB@@ difH`J@PAJUuJjjj`@ eMJA@Hz@ dg~H`DC@AIgffoeVvjjjjdiK@@ !BpEeTQIh_iVC`y]MgOzZTa@EB@JlYw}~`dBexBn{yVBdiHa}|@NH@~T_[^Ta@FbGsTn{]}yQ}Tn}|YYVeG}}Y =v;xzvzyvzDfUvzvzMTTvfjrkjxztn7un_hDIjE0EjgaS_8FTyuDoQdKlXm53AkJdRF9p141JVY0V0FV 46894 edV\L@@DMC`Ah\bbTTTTTbdRRsfNtRTfe`PWQTpLKUMAUUPUQUUUQH\HJ@@ 102932 = 110 nM Ki 0.28 14.88 12.49 |#|0:46894 Homo sapiens 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ difH`J@PAJUuJjjj`@ eMBD@ch@ eMJA@Hz@ dg~H`DC@AIgffoeVvjjjjdiK@@ !BktCI_peiMCFozS@Oy|I_yL@zW|I_zS_EhM`tNZd`YCfjTMPkG~lwpe@bTCiTMeokLBVozsdkeCYSqekO~lsqe =v;xzvzyvzEfUvzvzMyTvfjrkjxzxn7unbhDtjE0EjgLS_9wTyuDovvKlYn53AkRdRI9pGJ1JVY4#V 46894 ed^\L@@DMM`Ih\bbbbTRfdTbRsTJtrS@facdTWSRpLKULuAUUATUUUTVEADeDQ@@ 511139 = 1 nM Ki 0.36 19.41 18.51 |#|0:46894 Homo sapiens 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ difH`J@PAJUuJjjj`@ fhiaA@D@p@R@LbbfTRdTaUZpVjZjjjlTHyQXbED eMJA@Hz@ fhiaA@D@p@R@LbbfTRdTaUZpVjZjjjlTHyQXbED !BpEeTQIh_iVC`y]MgOzZTa@EB@JlYxI@i^@kn~U`bGvdiO@Cb@OeGyRD@[~H_MR{mwweG}|YUKoeGvUoUKl =v;xzvzyvzDfUvzvzMTLvfjMkjxUtn7mnW_BGjE0Cjg6S_0FTyuDoOdKlXm53@kJdRF9_141JVY0V0FV 46894 e`R\L@@DME`FolbbTTTRdTbRsfvtRTfaggeVWSwsUMAUUATUUUTRGB|`@ 103886 = 11 nM Ki 0.34 18.10 14.28 |#|0:46894 Homo sapiens 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 46 (11), 2110-2116 (2003) 12747783 10.1021/jm020329q f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ difH`J@PAJUuJjjj`@ eMJA@Hz@ dg~H`DC@AIgffoeVvjjjjdiK@@ !BhBw@ja\mtA@Iz@dCVw@gzmpJ`^amd}Cazgx@mwtw_j`~bC@ioyP@z[YLhPPg^@@WsH`g\@`X@APg\ =vzv;WzyvzXf5IzvdHiqz@CnkisvRe7gnb9DlnDF5eZAQW9BqTu4kQtJY3N12QcBcJ03mG61J0n$V 46746 e`ZTL@@KE`FolbbbbbTTTVRNfcTRRgfedUVWSPswsPR@E@ADUUTPU@UP@@ 374473 = 0.28 nM Ki 0.41 22.40 21.86 |#|0:46746 Cavia porcellus 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 J. Med. Chem. 41 (26), 5177-5187 (1998) 9857088 10.1021/jm9801197 f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ dcNDPJAY@M@DiWV\jjjjjcb@@ eFBH@c@@ dcNDPJAY@M@DiWV\jjjjjcb@@ dk\H`@p@rJJZIQDYtv`@@@@@ !BRGw~otbBMwuH__z@RKvHC\BrHHZXAbS@G{}RI`l_k~BbHJHbCw}rLa|`hbA`H`}Ta~_|c|bCvHoTc| =fzSxxxxMJAzUQ8lYO@Q7EF1hYeeBPzXEAX53Pnf6FWW0@OVO0JRlAovEUYHtA2AYZcL01c511J0WF#V 46906 eodTBD@EAiFng`H`bHrJJJYRqQQI[IQZYK`RsqHjyzBHFhFBJZjhb@@@ 116664 = 14 nM Ki 0.35 17.02 12.92 |#|0:46906 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 Bioorg. Med. Chem. Lett. 6 (19), 2263-2268 (1996) 10.1016/0960-894X(96)00426-X f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ dmtHpIBHJHT@RYfvxXH`X@@ eFBH@c@@ deVD`DBV@DfYWFVjjh@@ eMJA@Hz@ !BFLHxg[{P_nXXkabIvK~TKxpvFKGXoxpnNw~LL_mnBKXxknDvAtQ]abQ[~{QCa]_tVz`Mldn|Rz@@ =fzSxxxxMJAzUQ8lYO@Q7EF1hYeeBPzXEAX53Pnf6F1W0@OVO0JRlAovEUYHGA2AYZcL01c511J0VF#V 46906 eghTLD@INjfk`H`bHRYffYWugmVACGHlckhHHjA`bfjjH`@@ 116582 = 1046 nM Ki 0.27 13.37 13.69 |#|0:46906 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 Bioorg. Med. Chem. Lett. 6 (19), 2263-2268 (1996) 10.1016/0960-894X(96)00426-X f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ deT@p@bBbI@DfYoXXHH`@@ eFBH@c@@ deVD`DBV@DfYWFVjjh@@ eMJA@Hz@ !BJKpHwTF@OkHoG_BJKsA`M^COhC`ziLXhBH_ZrXozH@h`B_XbH_W~b@I}bDa}ow{|RGvH_Xc|R@ =fzOxxxlMJAMIQ0lWO@H26F0hYeeBPzX59X13Plf6FWV0@OV90JRl@ovETYFtA2AYZcL01c511J0WF#V 46906 eghTLD@ENiFk`H`bHrJJJYRqQQI[IISI\BV^IEGWPQ@u@pQUUTQ@@@ 116551 = 12 nM Ki 0.36 17.71 18.13 |#|0:46906 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 Bioorg. Med. Chem. Lett. 6 (19), 2263-2268 (1996) 10.1016/0960-894X(96)00426-X f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ dmtHpIBHJHT@RYfvxXH`X@@ eFBH@c@@ difH`J@PAJUuJjjj`@ eMJA@Hz@ !BFLJ~LCa]nFHgXmabYtKXG\\]ocCXXl]bmBx{_{Pq~vxXmcbntSX{S}EvNIEO{nDNAuQ[i@vzR{qKh@ =fzSxxxxMJAzUQ8lYO@Q7EF1hYeeBPzXEAX53Pnf6FWW0@OVO0JRlAovEUYHtA2AWZcL01c511J0WF#V 46906 eodTBD@EAiFng`HcbHrJJIQQqQQI[IQZYI`RsqHjyz@bFhFBJZjhb@@@ 116494 = 59 nM Ki 0.32 15.67 11.90 |#|0:46906 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 Bioorg. Med. Chem. Lett. 6 (19), 2263-2268 (1996) 10.1016/0960-894X(96)00426-X f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ dmtHpIBHzHT@RYefXXBHX@@ eFBH@c@@ deVD`DBV@DfYWFVjjh@@ eMJA@Hz@ !BDJhVpGaKDJkSVJddLiA@@`}[FaP_`K[uVxR|a|bCseXFCJJS~iwB}wrZouPa|i^@knx@Wwh ;rUbtKdu5w4GEbUNVpVN@P1ZF09Y8@4HvXK8iF3uk16FWV0@OV90JJl9Vd9RYFd90AWZcL!85W1J01F#V 46906 ek`XB@@D@AiedfYfYeWg[qEGD`jbnfj@F@B@Hfj@@@@ 116324 = 142 nM Ki 0.32 17.67 11.90 |#|0:46906 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 Bioorg. Med. Chem. Lett. 6 (19), 2263-2268 (1996) 10.1016/0960-894X(96)00426-X f`q`C`F@BRXHbEScYA]x~`TfYnY}yKQhHbJja@@ dk\H`@p@rJJZIQDYtv`@@@@@ eFBH@c@@ gGPh@j@ILkU@@ eMJA@Hz@ !BFLI~TMb]IzHxhmbbqyu~LMb]vJKGho{PNAw~tL\]NBKXXknDvIuQ]bbAW~{aMa]N`@ ;rUbtKdu5w4GEbUNVpVN@P1ZF09Y@@4HvXK8iF3uk96FWV0@OV90JJl9Vd9TYFdA0AWZVL!85W1J01F#V 46906 feg`R@A\jwhHcHhheDYhhdmdhlrQgQsA@qPLDTuD@@@ 116007 = 397 nM Ki 0.34 17.22 11.13 |#|0:46906 259 Cannabinoid CB2 receptor Homo sapiens Target is a single protein chain P34972 Bioorg. Med. Chem. 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